One Pot Multicomponent Synthesis of Pyranopyrazoles using Tetra Butyl Ammonium Bromide as Catalyst in Aqueous Media
نویسندگان
چکیده
منابع مشابه
Tetra-N-Butyl ammonium hydroxide mediated one-pot synthesis of pyrano [2, 3-d] pyrimidinone Derivatives
Tetra-N-Butyl Ammonium Hydroxide was used as a catalyst for one-pot, three component condensation reactions consisting of aromatic aldehydes, malononitrile and barbituric acid in ethanol:water solvent system at 60oC. Current method has major advantages like mild reaction conditions with simple operation, high yields, by using a less toxic and lower costlier catalyst.In conclusion, we have explo...
متن کاملtetra-n-butyl ammonium hydroxide mediated one-pot synthesis of pyrano [2, 3-d] pyrimidinone derivatives
tetra-n-butyl ammonium hydroxide was used as a catalyst for one-pot, three component condensation reactions consisting of aromatic aldehydes, malononitrile and barbituric acid in ethanol:water solvent system at 60oc. current method has major advantages like mild reaction conditions with simple operation, high yields, by using a less toxic and lower costlier catalyst.in conclusion, we have explo...
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1 Department of Pharmaceutical Sciences, Singhania University, Jhujhunu-333515, Rajasthan, India. 2 National Institute of Pharmaceutical Education & Research, Raebareli229010, Uttar Pradesh, India. A b s t r a c t Starting from different ketones 1a-1f, aldehyde 2a-2g, and acetonitriles 3a-3d we synthesize some bioactive βAcetamido carbonyl compounds 4a-4h. We also attempted to synthesize these ...
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Cis-polybutadiene was functionalized using in–situ generated DMD as oxidant and tetra-n-butyl ammonium bromide as phase transfer catalyst (PTC). The epoxidation process was investigated by 1HNMR spectroscopy. 1HNMR spectrum analysis of products confirms the absence of ring opening side products in epoxidation reaction. Various factors such as reaction temperature, reaction time and the concentr...
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Spirooxindoles are important synthetic targets possessing extended biological activity and drug discovery applications.The development of multicomponent reactions designed to produce elaborate biologically active compounds has become an important area of research in organic, combinatorial, and medicinal chemistry. in this Manuscript, a facile and efficient multicomponent synthesis of functional...
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ژورنال
عنوان ژورنال: International Journal For Research in Applied Sciences and Biotechnology
سال: 2018
ISSN: 2349-8889
DOI: 10.31033/ijrasb.5.5.5